The 2015 CLEO Conference and Exposition concluded today with 4,400 attendees, 226 exhibitors and 1380 presentations from around the world. Conference and exhibition programming provided attendees with valuable insights into a broad range of topics such as optical microscopy for brain imaging, three dimensional printing and single-photon nonlinear optics. CLEO 2015 took place 10-15 May at the San Jose McEnery Convention Center in San Jose, California, USA.